Anti X-Ray Repair Cross Complementing 6 XRCC6 Antibody

 

Immunology
formalin fixed tissue

G22P1; X-ray fix cross-complementing protein ; 5′ -deoxyribose-5-phosphate lyase Ku70; 5′ -dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70-kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6. XRCC6; G22P1; X-ray fix cross-complementing protein 6; 5′ -deoxyribose-5-phosphate lyase Ku70; 5′ -dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase two subunit 1; ATP-dependent DNA helicase II 70-kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells . 5′ -deoxyribose-5-phosphate lyase Ku70; 5′ -dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70-kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells .
1B). These proteins could form complexes to regulate the activities of these TR isoforms via direct contact with TR mutant isoforms or through being part of large complexes (secondary regulators) (17). Analysis of the functions of the mutant-associated proteins demonstrates that these proteins were involved in chromatin remodeling, transcription regulation, RNA splicing/modification, protein translation, DNA repair, ubiquitination/proteasome, mobile cycle/apoptosis, chaperone, enzymes, and protein trafficking (Tables 2 and 3). These data imply that common regulatory proteins could regulate the actions of mutant TR isoforms but could be led through an subset of nuclear proteins that are regulatory.

Western
Western Blot

5″-deoxyribose-5-phosphate lyase Ku70 Compounds”-dRP lyase Ku70 antibody70 kDa subunit of Ku antigen antibodyATP dependent DNA helicase 2 subunit 1 antibodyATP dependent DNA helicase II 70 kDa subunit antibodyATP-dependent DNA helicase 2 subunit 1 antibodyATP-dependent DNA helicase II 70 kDa subunit antibodyCTC box binding factor 75 kDa subunit antibodyCTC box-binding factor 75 kDa subunit antibodyCTC75 antibodyCTCBF antibodyDNA repair protein XRCC6 antibodyG22P1 antibodyKu 70 antibodyKu autoantigen 70kDa antibodyKu autoantigen p70 subunit antibodyKu autoantigen, 70kDa antibodyKu p70 antibodyKu70 DNA binding element of DNA-dependent protein kinase complex (thyroid autoantigen 70 kDa antibodyKup70 antibodyLupus Ku autoantigen protein p70 antibodyML8 antibodyThyroid autoantigen 70kD(Ku antigen) antibodyThyroid autoantigen antibodyThyroid Lupus autoantigen antibodyThyroid Lupus autoantigen p70 antibodyThyroid-lupus autoantigen antibodyTLAA antibodyX ray repair complementing defective repair in Chinese hamster cells 6 antibodyX-ray repair complementing defective repair in Chinese hamster cells 6 antibodyX-ray fix cross-complementing protein 6 antibodyXRCC 6 antibodyXRCC6_HUMAN antibody. 5″-deoxyribose-5-phosphate lyase Ku70; 5″-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 1; ATP dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase two subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku 70; Ku autoantigen p70 subunit; Ku autoantigen, 70kDa; Ku p70; Ku70; Ku70 DNA binding element of DNA-dependent proteinkinase complicated (thyroid autoantigen 70 kDa; Kup70; Lupus Ku autoantigen protein p70; ML8; Thyroid autoantigen 70kD (Ku antigen); Thyroid autoantigen; Thyroid lupus autoantigen; Thyroid lupus autoantigen p70; Thyroid-lupus autoantigen; TLAA; X ray repair complementing defective repair in Chinese hamster cells ; X-ray repair complementing defective repair in Chinese hamster cells ; X-ray fix cross-complementing protein ; XRCC 6; Xrcc6; XRCC6_HUMAN; ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II, 70 kDa subunit, X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa), X-ray fix cross-complementing protein 6, 5′-dRP lyase Ku70, 5′-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, DNA repair protein XRCC6, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, lupus Ku autoantigen protein p70, thyroid autoantigen 70kD (Ku antigen), thyroid autoantigen 70kDa (Ku antigen), thyroid-lupus autoantigen p70, 5′-dRP/AP lyase Ku70, CTC75, CTCBF, Ku p70, ku autoantigen protein p70 homolog, thyroid autoantigen 70 kDa, Ku70 DNA-binding part of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa), thyroid autoantigen, X-ray repair cross-complementing protein 5. X-ray fix cross-complementing protein , 5′ -deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase two subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chinese hamster cells , XRCC6_HUMAN.

X-ray fix cross-complementing protein 6

In presense of 5′ -deoxyribose-5-phosphate lyase Ku70, 5′ -dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase two subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1. X-ray fix cross-complementing protein (EC 3.6.4. -) (5′ -deoxyribose-5-phosphate lyase Ku70) (5′ -dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase two subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6), XRCC6, G22P1. X-ray repair cross-complementing protein , 3.6.4. -5′ -deoxyribose-5-phosphate lyase Ku70, 5′ -dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1.

Ku70

Ku69; X-ray repair cross-complementing 6 (XRCC6); Lupus Ku autoantigen protein p70; ATP-dependent DNA helicase two subunit 1; X-ray repair complementing defective repair in Chinese hamster cells 6. Ku80; Ku86; X-ray repair cross- complementing 5 (XRCC5); Lupus Ku autoantigen protein p80; X-ray repair complementing defective repair in Chinese hamster cells 6; ATP-dependent DNA helicase 2 subunit 2. 17 2 subunit 2. Ku70/80 heterodimer; Ku70/80; Ku(p70/p80); ku heterodimer. Interacts (through N-terminus) with HSF1 (via N-terminus); this interaction is direct and averts XRCC5/XRCC6 heterodimeric binding and non-homologous end joining (NHEJ) fix activities induced by ionizing radiation (IR) (PubMed: 26359349). Section of this HDP-RNP complex composed of HEXIM1, PRKDC, XRCC5, XRCC6, paraspeckle proteins (SFPQ, NONO, PSPC1, RBM14, and MATR3) and NEAT1 RNA (PubMed: 28712728). The originator of ab2620 and ab2624 (Ku70 antibodies) has informed us that the peptide sequences used to generate these products are considered commercially sensitive and this information cannot be published at this time.

-; EC 3.6.4. -; ATP-dependent DNA helicase II 70-kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells ; CTC box-binding factor 75 kDa subunit; 70 kDa subunit of Ku antigen; CTC75; 5′ -deoxyribose-5-phosphate lyase Ku70; KU70; TLAA; 5′ -dRP lyase Ku70; CTCBF; ML8; G22P1; X-ray fix cross-complementing protein 6; ATP-dependent DNA helicase two subunit 1; Ku70. 5′ -deoxyribose-5-phosphate lyase Ku70; 5′ -dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70-kDa subunit; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; D22S731; EC 3.6.4. -; EC 4.2.99. -; G22P1; G22P1Ku70; Ku autoantigen p70 subunit; Ku autoantigen, 70kDa; Ku70; ML8; ML8,70 kDa subunit; thyroid-lupus autoantigen p70; Thyroid-lupus autoantigen; TLAA; TLAAD22S671; X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6; X-ray repair cross-complementing protein ; XRCC6. X-ray repair cross-complementing protein (EC 3.6.4. -) (5′ -deoxyribose-5-phosphate lyase Ku70) (5′ -dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells )

Ku (p70): 70kDa subunit of Ku antigen; ATP dependent DNA helicase two subunit 1; ATP-dependent DNA helicase II 70kDa subunit; CTC box-binding variable 75kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku autoantigen, 70kDa; Ku70; Kup70; Lupus Ku autoantigen protein p70; ML8; Thyroid autoantigen 70kD (Ku antigen); Thyroid-lupus autoantigen (TLAA); X-ray fix cross-complementing protein (XRCC6) Ku (p80): 86kDa subunit of Ku antigen; ATP dependent DNA helicase two subunit 2; ATP dependent DNA helicase II 86Kd subunit; ATP-dependent DNA helicase II 80kDa subunit; CTC box-binding factor 85kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; KARP1; Ku autoantigen 80kDa; Ku80; Ku86 autoantigen related protein 1; KUB2; Lupus Ku autoantigen protein p86; Nuclear factor IV (NFIV); Thyroid-lupus autoantigen (TLAA); X-ray repair cross-complementing protein 5 (XRCC5) XRCC6; X-ray repair complementing defective repair in Chinese hamster cells ; ML8; KU70; TLAA; CTC75; CTCBF; G22P1; X-ray fix cross-complementing protein 6; 5-dRP lyase Ku70; Ku autoantigen, 70kDa; DNA repair protein XRCC6; Ku autoantigen p70 subunit; BioVision develops and supplies a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Mobile Pressure, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc..

what are the other names for X-Ray Repair Cross Complementing 6?

XRCC6 is known as 5 -dRP lyase Ku70, 5 -dRP/AP lyase Ku70, 70 kDa subunit of Ku antigen, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, Ku70, Ku70 XRCC6, Thyroid-lupus autoantigen, TLAA, XRCC6, XRCC6, XRCC6. X-ray repair complementing defective repair 6DNA repair protein XRCC6. For example, among the two proteins commonly associated with TR mutant isoforms (see Table 2), two are understood to maintain large complexes (Table 3). Cell cycle and apoptosis-regulatory protein 1 was reported to associate with parts of the mediator and p160 coactivator complexes and is an integral regulator of this Legislature complex recruited to nuclear receptor target genes in response to hormones (27). It is also a book component of Wnt/β-catenin indicating that plays a significant role in transcriptional regulation by β-catenin (28). KIF11 (kinesin family number 11) is a motor protein which belongs to the kinesin-like protein family engaged in several types of spindle dynamics including chromosome positioning, centrosome separation, and institution of a bipolar spindle during cell mitosis.

Genetic analysis reveals different functions for the products of the thyroid hormone receptor α locus. The preparation of nuclear and cytoplasmic extracts of FH-βPV, FH-αPV, and control cells has been carried out similarly as explained previously by Furuya et al. (37). The Western blot analysis was performed as described by Furumoto et al. (38) using the proper antibodies: monoclonal anti-PV antibody (two μg /ml) (37), monoclonal anti-Flag antibody (M2) (F-3165, 5 μg/ml; Sigma, Inc.), rabbit anti-PARP antibody (1:1,000 dilution) (sc-7150; Santa Cruz Biotechnology, Inc., Santa Cruz, CA), mouse anti-α-tubulin antibody (1:6000 dilution) (T6199, Sigma), mouse monoclonal antitransducin (β)-like 1 X-linked receptor 1 antibody (TBL1XR1) (1:1000 dilution) (sc-100908), rabbit polyclonal antieukaryotic initiation factor 4B antibody (eIF4B) (1:1000 dilution) (catalog no. 3592; Cell Signaling Technology, Danvers, MA), mouse monoclonal anti-HSPA1B (1:1000 dilution) (BD Transduction Laboratories, Lexington, KY), mouse monoclonal anti-XRCC5 (p80) Ab (1:200 dilution) (catalog no. For instance, the two TR mutant isoforms may be included in chromatin-remodeling functions through the commonly related proteins, including PRMT5 (protein arginine methyltransferase 5), XRCC5 (ATP-dependent DNA helicase II, 80-kDa subunit), and XRCC6 (X-ray repair complementing defective repair in Chinese hamster 6), whereas the chromatin-remodeling activity of TRα1PV could be mediated preferentially by complexing with CHD4 (chromodomain-helicase-DNA-binding protein 4) and also TRβ1PV by ACTB (actin β) (Table 2). Similarly, the transcription task of both TR mutant isoforms may be controlled through institution with the common atomic protein (cell cycle- and apoptosis-regulatory protein ), whereas the of TRα1PV could be preferentially controlled to complicated with the NCoR1 and/or with 10 other proteins (primary and/or secondary regulators) listed in column 3, row 3 of Table 2 together, these data clearly reveal that the activities of TR mutant isoforms may be preferentially directed by a subset of nuclear regulatory proteins.