X-Ray Crystallography of Antibodies by Dr. Eduardo A. Padlan

The detailed structure of antibodies and various fragments, including
isolated domains, from different isotypes and from different species has
become available from X-ray crystallography. Also, amino acid and
nucleotide sequence data have been obtained for thousands of different
chains (Kabat et al., 1991), so that a detailed correlation of primary and
three-dimensional structures can be performed. With this wealth of
information, we can now begin to understand the biological functions of
antibodies in structural terms.

Stationary High Stability X-Ray Equipment used: