Capillary Nano-immunoassay for Quantification of Proteins from CD138-purified Myeloma Cells

Capillary Nano-immunoassay for Quantification of Proteins from CD138-purified Myeloma Cells

Protein evaluation in bone marrow samples from sufferers with a number of myeloma (MM) has been restricted by the low focus of proteins obtained after CD138+ cell choice. A novel method based mostly on capillary nano-immunoassay may make it doable to quantify dozens of proteins from every CD138+ purified MM pattern in an automatic method. Up to now, the information of protein degree in these cells was restricted as a result of a comparatively small amount of pattern is on the market after the diagnostic process. Moreover, the pattern usually is required for nucleic acids evaluation.

We have developed the process for acquiring proteins from bone marrow samples preserved in RLT+ buffer, and now we have efficiently utilized this method for the quantification of proteins within the setting of sufferers with MM. Proteins are extracted from RLT+ buffer, the content material is quantified by whole protein assay with WES machine and eventually, the actual protein expression degree is evaluated utilizing particular antibodies by capillary nano-immunoassay with WES machine. The current protocol permits us to quantify many proteins from a restricted quantity of pattern, with out shedding the chance to acquire nucleic acids on the identical time. Proteins are quantified robotically in an assay with a low chance of human errors, which makes it a useful gizmo for biomarkers improvement.

Super-resolution Microscopy-based Bimolecular Fluorescence Complementation to Study Protein Complex Assembly and Co-localization

Numerous experimental approaches exist to check interactions between two subunits of a big macromolecular complicated. However, most strategies don’t present spatial and temporal details about binding, that are crucial for dissecting the mechanism of meeting of nanosized complexes in vivo. While latest advances in super-resolution microscopy methods have supplied insights into organic buildings past the diffraction restrict, most require in depth experience and/or particular pattern preparation, and it’s a problem to increase past binary, two colour experiments.

Using HyVolution, a super-resolution method that mixes confocal microscopy at sub-airy unit pinhole sizes with computational deconvolution, we achieved 140 nm decision in each dwell and stuck samples with three colours, together with two fluorescent proteins (mTurquoise2 and GFP) with important spectral overlap that had been distinguished by means of shifting the excitation wavelength away from widespread wavelengths. By combining HyVolution super-resolution fluorescence microscopy with bimolecular fluorescence complementation (SRM-BiFC), we describe a brand new assay succesful of visualizing protein-protein interactions in vivo at sub-diffraction decision. This methodology was used to enhance our understanding of the ordered meeting of the Saccharomyces cerevisiae spindle pole physique (SPB), a ~1 giga-Dalton heteromeric protein complicated fashioned from 18 structural parts current in a number of copies. We suggest that SRM-BiFC is a robust device for examination of direct interactions between protein complicated subunits at sub-diffraction decision in dwell cells.

Capillary Nano-immunoassay for Quantification of Proteins from CD138-purified Myeloma Cells

Interaction between Borrelia miyamotoi variable main proteins Vlp15/16 and Vlp18 with plasminogen and complement

Borrelia miyamotoi, a relapsing fever spirochete transmitted by Ixodid ticks causes B. miyamotoi illness (BMD). To evade the human host´s immune response, relapsing fever borreliae, together with B. miyamotoi, produce distinct variable main proteins. Here, we investigated Vsp1, Vlp15/16, and Vlp18 all of that are at present being evaluated as antigens for the serodiagnosis of BMD. Comparative analyses recognized Vlp15/16 however not Vsp1 and Vlp18 as a plasminogen-interacting protein of B. miyamotoi. Furthermore, Vlp15/16 certain plasminogen in a dose-dependent vogue with excessive affinity.
Binding of plasminogen to Vlp15/16 was considerably inhibited by the lysine analog tranexamic acid suggesting that the protein-protein interplay is mediated by lysine residues. By distinction, ionic energy didn’t impact binding of plasminogen to Vlp15/16. Of relevance, plasminogen certain to the borrelial protein cleaved the chromogenic substrate S-2251 upon conversion by urokinase-type plasminogen activator (uPa), demonstrating it retained its physiological exercise. Interestingly, additional analyses revealed a complement inhibitory exercise of Vlp15/16 and Vlp18 on the choice pathway by a Factor H-independent mechanism. More importantly, each borrelial proteins shield serum delicate Borrelia garinii cells from complement-mediated lysis suggesting a number of roles of these two variable main proteins in immune evasion of B. miyamotoi.

Goat Anti Feline Leukaemia Virus P27 Polyclonal Antibody

DPBT-66847GF 1 ml
EUR 1033.2

Mouse Anti Feline Leukaemia Virus P27 Monoclonal Antibody

DMABT-51280MF 0.2 mg
EUR 920.4

Mouse Anti Feline Leukaemia Virus P27 Monoclonal Antibody

DMABT-51281MF 0.25 mg
EUR 920.4

Feline Leukaemia Virus p15E Antibody

GWB-93501E 0.25 mg Ask for price

Feline Leukaemia Virus gp70 Antibody

GWB-Q00936 0.25 mg Ask for price

Feline Leukaemia Virus p15E (FeLV p15E) Antibody

abx414340-025mg 0.25 mg
EUR 811.2

Feline Leukaemia Virus p15E (FeLV p15E) Antibody

abx414340-200l 200 µl
EUR 600

Feline Leukaemia Virus gp70 (FeLV gp70) Antibody

abx413483-025mg 0.25 mg
EUR 710.4

Feline Leukaemia Virus gp70 (FeLV gp70) Antibody

abx413483-200l 200 µl
EUR 512.5

Mouse Anti Feline Leukaemia Virus P15e Monoclonal Antibody

DMABT-51278MF 0.25 mg
EUR 920.4

OASA00710-250UG - FELINE LEUKAEMIA VIRUS gp70 Antibody

OASA00710-250UG 0.25mg
EUR 479

OASA00712-250UG - LEUKAEMIA VIRUS p15E Antibody

OASA00712-250UG 0.25mg
EUR 519

Feline Leukemia Virus p27 antibody

10-1520 100 ug
EUR 250
Description: Mouse monoclonal Feline Leukemia Virus p27 antibody

Feline Leukemia virus p27 antibody

10-F05A 250 ug
EUR 257
Description: Mouse monoclonal Feline Leukemia virus antibody

Feline Leukemia Virus p27 antibody

10-F05C 250 ug
EUR 173
Description: Mouse monoclonal Feline Leukemia Virus p27 antibody

Feline Leukemia Virus p27 antibody

20-FG32 1 mg
EUR 115
Description: Goat polyclonal Feline Leukemia Virus p27 antibody

Feline Leukemia Virus p27 antibody (HRP)

60-5006 1 ml
EUR 425
Description: Goat polyclonal Feline Leukemia Virus p27 antibody (HRP)

Feline Leukemia Virus p27 antibody (biotin)

60-5007 1 ml
EUR 405
Description: Goat polyclonal Feline Leukemia Virus p27 antibody (biotin)

Feline Leukemia Virus (FeLV) p27, Antibody

GWB-8ECA50 0.25 mg Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024235-400l 400 µl Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024235-80l 80 µl
EUR 1550

Feline Leukemia Virus (FeLV) p27 Antibody

abx024236-400l 400 µl Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024236-80l 80 µl
EUR 1550

Mouse Anti Feline Leukemia Virus P27 Antibody (7226)

MAB12386-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7226)

Mouse Anti Feline Leukemia Virus P27 Antibody (7226)

MAB12386-500 0.5
EUR 692.74
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7226)

Mouse Anti Feline Leukemia Virus P27 Antibody (7228)

MAB12387-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7228)

Mouse Anti Feline Leukemia Virus P27 Antibody (7228)

MAB12387-500 0.5
EUR 692.74
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7228)

OAEF00269-500UG - Feline Leukemia Virus (p27) Antibody

OAEF00269-500UG 500ug
EUR 628

OAEF00270-500UG - Feline Leukemia Virus (p27) Antibody

OAEF00270-500UG 500ug
EUR 628

Mouse Anti Feline Leukemia Virus P27 Antibody (M452)

MAB12388-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M452)

Mouse Anti Feline Leukemia Virus P27 Antibody (M452)

MAB12388-500 0.5
EUR 691.46
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M452)

Mouse Anti Feline Leukemia Virus P27 Antibody (M453)

MAB12389-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M453)

Mouse Anti Feline Leukemia Virus P27 Antibody (M453)

MAB12389-500 0.5
EUR 691.46
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M453)

Feline Leukemia Virus p27 protein

30-1928 100 ug
EUR 443
Description: Recombinant FeLV p27 protein with his tag

Mouse antibody for Feline Leukemia virus FeLv p27

7218 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Mouse antibody for Feline Leukemia virus FeLv p27

7226 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Mouse antibody for Feline Leukemia virus FeLv p27

7228 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Feline Leukemia Virus p27 Recombinant

rAP-5199 Inquiry Ask for price

Recombinant Feline Leukemia Virus p27 Antigen

E41H082 100ug
EUR 395

OPEF01530-100UG - Recombinant Feline Leukemia Virus (p27) Antigen

OPEF01530-100UG 100ug
EUR 635

Feline Leukemia virus antibody

10C-CR1297M1 100 ug
EUR 295
Description: Mouse monoclonal Feline Leukemia virus antibody

Feline Leukemia Virus (FeLV), Antibody

GWB-925711 0.25 mg Ask for price

Feline Leukemia Virus gp70 antibody

10-F07A 250 ug
EUR 392.4
Description: Mouse monoclonal Feline Leukemia Virus gp70 antibody

Feline Leukemia Virus gp70 antibody

10-F07B 250 ug
EUR 392.4
Description: Mouse monoclonal Feline Leukemia Virus gp70 antibody

Feline Leukemia Virus gp70, Antibody

GWB-3603CB 0.25 mg Ask for price

Feline Leukemia Virus gp70, Antibody

GWB-1D8338 0.25 mg Ask for price

Feline leukemia virus

PCR-V176-PCRV17648R PCR-V176-48R
EUR 485

Feline leukemia virus

PCR-V176-PCRV17696R PCR-V176-96R
EUR 685

Feline leukemia virus

Oneq-V176-OneqV176100R Oneq-V176-100R
EUR 1028

Feline leukemia virus

Oneq-V176-OneqV176150R Oneq-V176-150R
EUR 1438

Feline leukemia virus

Oneq-V176-OneqV17650R Oneq-V176-50R
EUR 728

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

20-abx141749
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B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx034450-400ul 400 ul
EUR 627.6

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx034450-80l 80 µl
EUR 343.2

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

20-abx004168
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B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx230837-100ug 100 ug
EUR 610.8

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

20-abx320128
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B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx004168-100l 100 µl
EUR 387.5

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx004168-20l 20 µl
EUR 175

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx004168-50l 50 µl
EUR 275

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx034450-100g 100 µg
EUR 281.25

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx230837-100g 100 µg
EUR 350

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx320128-100l 100 µl
EUR 350

B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

abx320128-50l 50 µl
EUR 237.5

Feline Leukemia Virus Monoclonal antibody(capture)

E41H121 100ug
EUR 695
Description: Available in various conjugation types.

Feline Leukemia Virus Monoclonal antibody (conjugate)

E41H122 100ug
EUR 695
Description: Available in various conjugation types.

Goat polyclonal antibody for Feline Leukemia virus

274 1 ml
EUR 386.26
Description: This is HRP conjugated goat polyclonal antibody against Feline Leukemia virus p27 for WB, ELISA.

Goat polyclonal antibody for Feline Leukemia virus

7221 1 ml
EUR 340.57
Description: This is goat polyclonal antibody against Feline Leukemia virus p27 for WB, ELISA.

Goat polyclonal antibody for Feline Leukemia virus

7227 1 ml
EUR 360.16
Description: This is Biotin conjugated goat polyclonal antibody against Feline Leukemia virus p27 for WB, ELISA.

Mouse antibody for Feline Leukemia virus FeLv gp70

7217 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv gp70 for WB, ELISA.

LEUKAEMIA INHIBITORY FACTOR

GWB-4ED8C0 0.005 mg Ask for price

LEUKAEMIA INHIBITORY FACTOR

GWB-6B0A86 0.01 mg Ask for price

Feline Leukemia Virus (FeLV) Antigen

DEFELVT4800 96
EUR 230

Feline Immunodeficiency Virus p24 Antibody

GWB-208BAD 2 ml Ask for price

Feline Immunodeficiency Virus p24 Antibody

GWB-C3B01D 0.2 mg Ask for price

Feline leukemia virus PCR kit

PCR-V176-48R 50T
EUR 987.6

Feline leukemia virus PCR kit

PCR-V176-96R 100T
EUR 1335.6

Feline leukemia virus RT PCR kit

RTq-V176-100R 100T
EUR 1573.2

Feline leukemia virus RT PCR kit

RTq-V176-150R 150T
EUR 2144.4

Feline leukemia virus RT PCR kit

RTq-V176-50R 50T
EUR 1155.6

Feline Leukemia Virus(FeLV) Antigen Test Card

C11161 15T Ask for price

Feline Leukosis Virus (FeLV) Antigen Test Card

C11441 15T Ask for price

Feline Leukemia Virus Real-time PCR

PZ1016 16T
EUR 64
Description: Blood

Feline Leukemia Virus Antigen Rapid Test Kit

abx092134-100l 100 µl
EUR 562.5

Feline Leukemia Virus Antigen Rapid Test Kit

abx092134-1ml 1 ml Ask for price

Feline Leukemia Virus Antigen Rapid Test Kit

abx092134-200l 200 µl Ask for price

Feline leukemia virus One-Step PCR kit

Oneq-V176-100R 100T
EUR 1932

Feline leukemia virus One-Step PCR kit

Oneq-V176-150R 150T
EUR 2646

Feline leukemia virus One-Step PCR kit

Oneq-V176-50R 50T
EUR 1410

Feline Immunodeficiency Virus Antibody (p24 gag)

GWB-AA7524 0.25 mg Ask for price

Feline Immunodeficiency Virus Antibody (p24 gag)

GWB-ABCB24 0.25 mg Ask for price

genesig Easy kit for Feline Leukemia Virus

Z-Path-FeLV-EASY 50 tests
EUR 410
Description: FeLV

Feline Herpes Virus Type 1 Antibody

GWB-B8A2E9 0.25 mg Ask for price

Feline Immunodeficiency Virus p24 Antigen (FIV p24) Antibody

abx411336-02mg 0.2 mg
EUR 710.4

Feline Immunodeficiency Virus p24 Antigen (FIV p24) Antibody

abx412988-2ml 2 ml
EUR 727.2

Feline Immunodeficiency Virus p24 Antigen (FIV p24) Antibody

abx411336-200g 200 µg
EUR 512.5

OASA00704-200UG - FELINE IMMUNODEFICIENCY VIRUS p24 Antibody

OASA00704-200UG 0.2mg
EUR 479

Feline Immunodeficiency Virus (FIV), Antibody

GWB-86DFD2 0.25 mg Ask for price

Feline Leukemia Virus Antigen (FeLv Ag) Rapid Test Kit

HG029 10 Tests/Kit
EUR 21
Description: Contents: (1) 10 Tests/Kit   (cassette,disposable dropper,desiccant) (2) 10 Assay buffer tubes (3) 10 Sterile swabs (4) 1 Instruction manual

Rat Common acute lymphocytic leukaemia antigen ELISA kit

E02C0678-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Common acute lymphocytic leukaemia antigen ELISA kit

E02C0678-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Common acute lymphocytic leukaemia antigen ELISA kit

E02C0678-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Common acute lymphocytic leukaemia antigen ELISA kit

E07C0678-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Common acute lymphocytic leukaemia antigen ELISA kit

E07C0678-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Common acute lymphocytic leukaemia antigen ELISA kit

E07C0678-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Common acute lymphocytic leukaemia antigen ELISA kit

E08C0678-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Common acute lymphocytic leukaemia antigen ELISA kit

E08C0678-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Common acute lymphocytic leukaemia antigen ELISA kit

E08C0678-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Common acute lymphocytic leukaemia antigen ELISA kit

E01A11091 96T
EUR 700
Description: ELISA

Feline Immunodeficiency Virus gp95 Antibody

GWB-1F051A 0.25 mg Ask for price

Feline Immunodeficiency Virus gp95 Antibody

GWB-30B103 0.25 mg Ask for price

Feline Immunodeficiency Virus Antibody (gp41)

GWB-B4D6F2 0.2 mg Ask for price

Feline Immunodeficiency Virus gp95 Antibody

GWB-E938E9 0.25 mg Ask for price

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

20-abx006544
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  • 100 ul
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Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVC2) Antibody

abx034469-400ul 400 ul
EUR 627.6

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVC2) Antibody

abx034469-80l 80 µl
EUR 343.2

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

20-abx322439
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  • 100 ul
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Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

20-abx322440
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  • 100 ul
  • 50 ul

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx006544-100g 100 µg
EUR 275

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx006544-10g 10 µg
EUR 175

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx006544-200g 200 µg
EUR 400

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVC2) Antibody

abx034469-100g 100 µg
EUR 281.25

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx322439-100g 100 µg
EUR 350

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx322439-50g 50 µg
EUR 250

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx322440-100g 100 µg
EUR 350

Feline Leukemia Virus Subgroup C Receptor-Related Protein 2 (FLVCR2) Antibody

abx322440-50g 50 µg
EUR 250

Goat Common acute lymphocytic leukaemia antigen ELISA kit

E01A46004 96T
EUR 700
Description: ELISA

Goat Common acute lymphocytic leukaemia antigen ELISA kit

E06C0678-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Common acute lymphocytic leukaemia antigen ELISA kit

E06C0678-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Common acute lymphocytic leukaemia antigen ELISA kit

E06C0678-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Feline Immunodeficiency Virus gp120 Antibody

GWB-C4000D 2 ml Ask for price

Mouse Common acute lymphocytic leukaemia antigen ELISA kit

E01A19832 96T
EUR 700
Description: ELISA

Human Common acute lymphocytic leukaemia antigen ELISA kit

E01A2330 96T
EUR 700
Description: ELISA

Mouse Common acute lymphocytic leukaemia antigen ELISA kit

E03C0678-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Common acute lymphocytic leukaemia antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
The objective of cryoEM is to find out the buildings of biomolecules from electron micrographs. In many instances the processing is simple and will be dealt with with routine protocols. In different instances, the properties and conduct of the specimen require adaptions to correctly interpret the info. Here I describe the protocols for analyzing the upper order assemblies of the retinal adhesion protein, retinoschisin (RS1), utilizing the Bsoft bundle. The protocols for micrograph preprocessing, 2D classification and 3D alignment and reconstruction observe the same old patterns for the bulk of cryoEM specimens. The interpretation of the outcomes is particular to the branched community of RS1 filaments. The 2D class averages are used to find out the relative positions of the RS1 molecules, thus defining the interacting interfaces within the community. The main interface of the linear filament is then additional examined by reconstructing the “unit cell” and becoming the molecular fashions.

SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation

SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation

Viral infection-induced activation of inflammasome complexes has each optimistic and unfavourable results on the host. Proper activation of inflammasome complexes induces down-stream effector mechanisms that inhibit viral replication and promote viral clearance, whereas dysregulated activation has detrimental results on the host. Coronaviruses, together with SARS-CoV and MERS-CoV, encode viroporins that activate the NLRP3 inflammasome, and the severity of coronavirus illness is related to the inflammasome activation.

Although the NLRP3 inflammasome activation is implicated in the pathogenesis of coronaviruses, these viruses should evade inflammasome-mediated antiviral immune responses to ascertain major replication. Screening of a complementary DNA (cDNA) library encoding 28 SARS-CoV-2 open studying frames (ORFs) confirmed that two nonstructural proteins (NSPs), NSP1 and NSP13, inhibited caspase-1-mediated IL-1β activation. NSP1 amino acid residues concerned in host translation shutoff and NSP13 domains answerable for helicase exercise have been related to caspase-1 inhibition. In THP-1 cells, each NSP1 and NSP13 considerably decreased NLRP3-inflammasome-induced caspase-1 exercise and IL-1β secretion. These findings point out that SARS-CoV-2 NSP1 and NSP13 are potent antagonists of the NLRP3 inflammasome.

The world problem to stop fungal spoilage and mycotoxin contamination on meals and feeds require the growth of recent antifungal methods. Filamentous fungi encode various antifungal proteins (AFPs), which supply an awesome potential for the management of contaminant fungi. In this research, 4 AFPs from Penicillium digitatum (PdAfpB) and Penicillium expansum (PeAfpA, PeAfpB and PeAfpC) belonging to courses A, B and C, have been examined towards a consultant panel of mycotoxin-producing fungi. They included a complete of 38 strains representing 32 totally different species belonging to the genera Alternaria, Aspergillus, Byssochlamys, Fusarium and Penicillium. PeAfpA exhibited a potent antifungal exercise, since the development of all examined fungi was utterly inhibited by concentrations starting from 0.5 to 16 μg/mL. PdAfpB and PeAfpB, though much less efficient than PeAfpA, confirmed important exercise towards most of the mycotoxigenic fungi examined.

Three-dimensional Reconstruction and Quantification of Proteins and mRNAs at the Single-cell Level in Cultured Cells

Gene expression is commonly regulated by the abundance, localization, and translation of mRNAs in each house and time. Being capable of visualize mRNAs and protein merchandise in single cells is essential to grasp this regulatory course of. The growth of single-molecule RNA fluorescence in situ hybridization (smFISH) permits the detection of particular person RNA molecules at the single-molecule and single-cell ranges. When mixed with immunofluorescence (IF), each mRNAs and proteins in particular person cells will be analyzed concurrently.

However, a exact and streamlined quantification methodology for the smFISH and IF mixed dataset is scarce, as present workflows largely deal with quantifying the smFISH knowledge alone. Here we element a way for performing sequential IF and smFISH in cultured cells (as described in Sepulveda et al., 2018 ) and the subsequent statistical evaluation of the smFISH and IF knowledge by way of three-dimensional (3D) reconstruction in a semi-automatic picture processing workflow. Although our methodology relies on analyzing centrosomally enriched mRNAs and proteins, the workflow will be readily tailored for performing and analyzing smFISH and IF knowledge in different organic contexts.SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation

Pathogenic LRRK2 regulates ciliation likelihood upstream of tau tubulin kinase 2 by way of Rab10 and RILPL1 proteins

Mutations that activate LRRK2 protein kinase trigger Parkinson’s illness. We confirmed beforehand that Rab10 phosphorylation by LRRK2 enhances its binding to RILPL1, and collectively, these proteins block cilia formation in quite a lot of cell sorts, together with affected person derived iPS cells. We have used live-cell fluorescence microscopy to establish, extra exactly, the impact of LRRK2 kinase exercise on each the formation of cilia triggered by serum hunger and the lack of cilia seen upon serum readdition. LRRK2 exercise decreases the total likelihood of ciliation with out altering the charges of cilia formation in R1441C LRRK2 MEF cells.

Cilia loss in these cells is accompanied by ciliary decapitation, and kinase exercise doesn’t change the timing or frequency of decapitation or the price of cilia loss however will increase the p.c of cilia which are misplaced upon serum addition. LRRK2 exercise, or overexpression of RILPL1 protein, blocks launch of CP110 from the mom centriole, a step usually required for early ciliogenesis; LRRK2 blockade of CP110 uncapping requires Rab10 and RILPL1 proteins and is because of failure to recruit TTBK2, a kinase wanted for CP110 launch. In distinction, deciliation likelihood doesn’t change in cells missing Rab10 or RILPL1 and depends on a definite LRRK2 pathway. These experiments present essential element to our understanding of the mobile penalties of pathogenic LRRK2 mutation and point out that LRRK2 blocks ciliogenesis upstream of TTBK2 and enhances the deciliation course of in response to serum addition.

Mouse Anti Feline Leukemia Virus P27 Antibody (7226)

MAB12386-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7226)

Mouse Anti Feline Leukemia Virus P27 Antibody (7226)

MAB12386-500 0.5
EUR 692.74
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7226)

Mouse Anti Feline Leukemia Virus P27 Antibody (7228)

MAB12387-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7228)

Mouse Anti Feline Leukemia Virus P27 Antibody (7228)

MAB12387-500 0.5
EUR 692.74
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (7228)

Mouse Anti Feline Leukemia Virus P27 Antibody (M452)

MAB12388-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M452)

Mouse Anti Feline Leukemia Virus P27 Antibody (M452)

MAB12388-500 0.5
EUR 691.46
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M452)

Mouse Anti Feline Leukemia Virus P27 Antibody (M453)

MAB12389-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M453)

Mouse Anti Feline Leukemia Virus P27 Antibody (M453)

MAB12389-500 0.5
EUR 691.46
Description: Mouse monoclonal antibody specific for Feline Leukemia Virus P27 (M453)

Mouse Anti Feline Leukaemia Virus P27 Monoclonal Antibody

DMABT-51280MF 0.2 mg
EUR 920.4

Mouse Anti Feline Leukaemia Virus P27 Monoclonal Antibody

DMABT-51281MF 0.25 mg
EUR 920.4

Mouse Anti Feline Leukaemia Virus P15e Monoclonal Antibody

DMABT-51278MF 0.25 mg
EUR 920.4

OASB02362-500UG - Feline CD5 Antibody

OASB02362-500UG 0.5mg
EUR 339

OASB02370-500UG - Feline CD4 Antibody

OASB02370-500UG 0.5mg
EUR 339

Feline FeLV antibody

10-2328 100 ug
EUR 476
Description: Mouse monoclonal Feline FeLV antibody for lateral flow

Feline FeLV antibody

10-2329 100 ug
EUR 167
Description: Mouse monoclonal Feline FeLV antibody for lateral flow

Mouse antibody for Feline Leukemia virus FeLv p27

7218 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Mouse antibody for Feline Leukemia virus FeLv p27

7226 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Mouse antibody for Feline Leukemia virus FeLv p27

7228 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv p27 for WB, ELISA.

Amylin (Feline) - Antibody

H-017-01 50 μl
EUR 238.68

Mouse antibody for Feline Leukemia virus FeLv gp70

7217 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Feline Leukemia virus FeLv gp70 for WB, ELISA.

OASB02365-100UG - Feline CD5 Antibody : PE

OASB02365-100UG 0.1mg
EUR 309

OASB02373-100UG - Feline CD4 Antibody : PE

OASB02373-100UG 0.1mg
EUR 309

OASB02363-500UG - Feline CD5 Antibody : FITC

OASB02363-500UG 0.5mg
EUR 479

OASB02371-500UG - Feline CD4 Antibody : FITC

OASB02371-500UG 0.5mg
EUR 479

Polyclonal Antibody to Feline Sarcoma Oncogene (FES)

PAJ109Hu01 100ul
EUR 245

Polyclonal Antibody to Feline Sarcoma Oncogene (FES)

PAJ109Mu01 100ul
EUR 252

OASB02364-500UG - Feline CD5 Antibody : Biotin

OASB02364-500UG 0.5mg
EUR 429

OASB02372-500UG - Feline CD4 Antibody : Biotin

OASB02372-500UG 0.5mg
EUR 429

Feline Coronavirus Antibody

GWB-526828 0.25 mg Ask for price

Feline Calicivirus Antibody

GWB-778DD5 0.25 mg Ask for price

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse)

4-PAJ109Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES)

Mouse Anti-Feline CD8, Antibody

GWB-281E04 0.5 mg Ask for price

Mouse Anti-Feline CD8, Antibody

GWB-ACF0F3 0.5 mg Ask for price

Mouse Anti-Feline CD8, Antibody

GWB-E3703F 0.1 mg Ask for price

Mouse Anti-Feline CD8, Antibody

GWB-EA3E29 0.5 mg Ask for price

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), PE

4-PAJ109Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with PE.

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), APC

4-PAJ109Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with APC.

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), Cy3

4-PAJ109Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with Cy3.

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), HRP

4-PAJ109Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with HRP.

Feline Leukemia virus antibody

10C-CR1297M1 100 ug
EUR 295
Description: Mouse monoclonal Feline Leukemia virus antibody

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), FITC

4-PAJ109Mu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with FITC.

Feline Calicivirus (FCV) Antibody

abx413481-025mg 0.25 mg
EUR 811.2

Feline Calicivirus (FCV) Antibody

abx413481-200l 200 µl
EUR 600

Canine/Feline Parvovirus Antibody

GWB-CD6051 0.25 mg Ask for price

Feline Coronavirus Antibody (Biotin)

GWB-624AC3 0.25 mg Ask for price

Feline Calicivirus Antibody (Biotin)

GWB-F6A2DA 0.25 mg Ask for price

Feline Anti-Leukemia Virus Antibody (Anti-FeLV) ELISA Kit

SL0026Fe - Ask for price

Feline IgA mouse monoclonal antibody, clone IgA9-6A, Purified

SM1508P 250 µg Ask for price

Feline IgG mouse monoclonal antibody, clone GPB2-2B1, Purified

AM01351PU-N 250 µg Ask for price

Feline IgG mouse monoclonal antibody, clone K62 2G4, Supernatant

SM1046 2 ml Ask for price

Feline Leukemia Virus (FeLV), Antibody

GWB-925711 0.25 mg Ask for price

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), Biotinylated

4-PAJ109Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with Biotin.

Feline Sarcoma Oncogene (FES) Polyclonal Antibody (Mouse), APC-Cy7

4-PAJ109Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Mouse Feline Sarcoma Oncogene (FES). This antibody is labeled with APC-Cy7.

Feline Leukemia Virus p27 antibody

10-1520 100 ug
EUR 250
Description: Mouse monoclonal Feline Leukemia Virus p27 antibody

Feline Leukemia virus p27 antibody

10-F05A 250 ug
EUR 257
Description: Mouse monoclonal Feline Leukemia virus antibody

Feline Leukemia Virus p27 antibody

10-F05C 250 ug
EUR 173
Description: Mouse monoclonal Feline Leukemia Virus p27 antibody

Feline Leukemia Virus p27 antibody

20-FG32 1 mg
EUR 115
Description: Goat polyclonal Feline Leukemia Virus p27 antibody

Feline Calicivirus mouse monoclonal antibody, clone SI-9, Biotin

SM1726B 250 µg Ask for price

Feline Leukemia Virus gp70 antibody

10-F07A 250 ug
EUR 392.4
Description: Mouse monoclonal Feline Leukemia Virus gp70 antibody

Feline Leukemia Virus gp70 antibody

10-F07B 250 ug
EUR 392.4
Description: Mouse monoclonal Feline Leukemia Virus gp70 antibody

Feline Anaplasma Antibody Test Card

C10712 15T Ask for price

Feline Leukaemia Virus p27 Antibody

GWB-2D8170 0.25 mg Ask for price

Feline Leukemia Virus gp70, Antibody

GWB-3603CB 0.25 mg Ask for price

Feline Leukemia Virus gp70, Antibody

GWB-1D8338 0.25 mg Ask for price

Feline Leukaemia Virus p27 Antibody

GWB-68298D 0.2 mg Ask for price

Amylin (Feline) - Purified IgG Antibody

G-017-01 400 μg
EUR 506.52

Feline Sarcoma Oncogene (FES) Antibody

20-abx112510
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  • 150 ul
  • 50 ul

Feline Sarcoma Oncogene (FES) Antibody

20-abx129036
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Feline Sarcoma Oncogene (FES) Antibody

20-abx129797
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Feline Sarcoma Oncogene (FES) Antibody

abx145934-100ug 100 ug
EUR 469.2

Feline Sarcoma Oncogene (FES) Antibody

abx015747-100ul 100 ul
EUR 493.2

Feline Sarcoma Oncogene (FES) Antibody

abx012141-100ul 100 ul
EUR 493.2

Feline Sarcoma Oncogene (FES) Antibody

20-abx013365
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Feline Sarcoma Oncogene (FES) Antibody

20-abx002015
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Feline Sarcoma Oncogene (FES) Antibody

20-abx211565
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  • 100 ul
  • 50 ul

Feline Sarcoma Oncogene (FES) Antibody

20-abx211566
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  • 100 ul
  • 50 ul

Feline Sarcoma Oncogene (FES) Antibody

20-abx325863
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  • 100 ug
  • 50 ug

Feline Sarcoma Oncogene (FES) Antibody

abx331773-100ul 100 ul
EUR 510

Feline Sarcoma Oncogene (FES) Antibody

20-abx320346
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  • 100 ul
  • 50 ul

Feline Leukaemia Virus gp70 Antibody

GWB-Q00936 0.25 mg Ask for price

Feline Leukaemia Virus p15E Antibody

GWB-93501E 0.25 mg Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx013365-100g 100 µg
EUR 237.5

Feline Sarcoma Oncogene (FES) Antibody

abx013365-10g 10 µg
EUR 43.75

Feline Sarcoma Oncogene (FES) Antibody

abx013365-200g 200 µg
EUR 312.5

Feline Sarcoma Oncogene (FES) Antibody

abx002015-100l 100 µl
EUR 400

Feline Sarcoma Oncogene (FES) Antibody

abx002015-20l 20 µl
EUR 175

Feline Sarcoma Oncogene (FES) Antibody

abx002015-50l 50 µl
EUR 275

Feline Sarcoma Oncogene (FES) Antibody

abx012141-100g 100 µg Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx012141-10g 10 µg
EUR 362.5

Feline Sarcoma Oncogene (FES) Antibody

abx012141-200g 200 µg Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx129036-100l 100 µl
EUR 275

Feline Sarcoma Oncogene (FES) Antibody

abx129036-1ml 1 ml
EUR 750

Feline Sarcoma Oncogene (FES) Antibody

abx129036-200l 200 µl
EUR 337.5

Feline Sarcoma Oncogene (FES) Antibody

abx129797-100l 100 µl
EUR 275

Feline Sarcoma Oncogene (FES) Antibody

abx129797-1ml 1 ml
EUR 775

Feline Sarcoma Oncogene (FES) Antibody

abx129797-200l 200 µl
EUR 350

Feline Sarcoma Oncogene (FES) Antibody

abx211565-100l 100 µl
EUR 350

Feline Sarcoma Oncogene (FES) Antibody

abx211565-50l 50 µl
EUR 250

Feline Sarcoma Oncogene (FES) Antibody

abx211566-100l 100 µl
EUR 350

Feline Sarcoma Oncogene (FES) Antibody

abx211566-50l 50 µl
EUR 250

Feline Sarcoma Oncogene (FES) Antibody

abx112510-100l 100 µl
EUR 612.5

Feline Sarcoma Oncogene (FES) Antibody

abx015747-1mg 1 mg
EUR 362.5

Feline Sarcoma Oncogene (FES) Antibody

abx145934-1096tests 10 × 96 tests Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx145934-596tests 5 × 96 tests Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx145934-96tests 96 tests
EUR 337.5

Feline Sarcoma Oncogene (FES) Antibody

abx215463-100g 100 µg Ask for price

Feline Sarcoma Oncogene (FES) Antibody

abx215463-25g 25 µg
EUR 350

Feline Sarcoma Oncogene (FES) Antibody

abx325863-100g 100 µg
EUR 250

Feline Sarcoma Oncogene (FES) Antibody

abx325863-50g 50 µg
EUR 187.5

Feline Sarcoma Oncogene (FES) Antibody

abx320346-100l 100 µl
EUR 350

Feline Sarcoma Oncogene (FES) Antibody

abx320346-50l 50 µl
EUR 237.5

Feline Parvovirus Antibody ELISA Kit

KE0018 96T
EUR 160
Description: Serum

Feline Toxoplasma Antibody ELISA Kit

PZ5024 96T
EUR 160
Description: Serum

Feline Coronavirus mouse monoclonal antibody, clone CCV2-2, Biotin

AM01094BT-N 250 µg Ask for price

Feline Herpesvirus Antibody ELISA Kit

KE0019 96T
EUR 160
Description: Serum

Feline Calicivirus Antibody ELISA Kit

KE0020 96T
EUR 160
Description: Serum

Goat Anti Feline Leukaemia Virus P27 Polyclonal Antibody

DPBT-66847GF 1 ml
EUR 1033.2

Feline Calicivirus (FCV) Antibody (Biotin)

abx413480-025mg 0.25 mg
EUR 895.2

Feline Calicivirus (FCV) Antibody (Biotin)

abx413480-200l 200 µl
EUR 675

Feline Herpes Virus Type 1 Antibody

GWB-B8A2E9 0.25 mg Ask for price

Feline Rabies IgG Antibody ELISA Kit

KE0012 96T
EUR 160
Description: Serum

OAEF00525-1MG - Feline Cortisol Antibody

OAEF00525-1MG 1mg
EUR 309

Feline Leukemia Virus (FeLV) p27, Antibody

GWB-8ECA50 0.25 mg Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024235-400l 400 µl Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024235-80l 80 µl
EUR 1550

Feline Leukemia Virus (FeLV) p27 Antibody

abx024236-400l 400 µl Ask for price

Feline Leukemia Virus (FeLV) p27 Antibody

abx024236-80l 80 µl
EUR 1550

Feline Coronavirus mouse monoclonal antibody, clone FIPV3-70, Purified

SM1870P 250 µg Ask for price

Feline Leukemia Virus p27 antibody (HRP)

60-5006 1 ml
EUR 425
Description: Goat polyclonal Feline Leukemia Virus p27 antibody (HRP)

Feline IgA goat polyclonal antibody, HRP

SP2012HRP 1 mg Ask for price

Feline IgM goat polyclonal antibody, HRP

SP2014HRP 1 mg Ask for price

Feline Immunodeficiency Virus p24 Antibody

GWB-208BAD 2 ml Ask for price

Feline Immunodeficiency Virus (FIV), Antibody

GWB-86DFD2 0.25 mg Ask for price

Feline Immunodeficiency Virus p24 Antibody

GWB-C3B01D 0.2 mg Ask for price

OAEF00794-1MG - Feline Parvovirus Antibody

OAEF00794-1MG 1mg
EUR 1683

OAEF00795-1MG - Feline Parvovirus Antibody

OAEF00795-1MG 1mg
EUR 1683

OAEF00853-1MG - Feline Parvovirus Antibody

OAEF00853-1MG 1mg
EUR 537

OAEF00854-1MG - Feline Parvovirus Antibody

OAEF00854-1MG 1mg
EUR 537

Feline IgM goat polyclonal antibody, FITC

SP2014F 1 mg Ask for price

Feline Immunodeficiency Virus gp95 Antibody

GWB-1F051A 0.25 mg Ask for price

Feline Immunodeficiency Virus gp95 Antibody

GWB-30B103 0.25 mg Ask for price

Feline Immunodeficiency Virus Antibody (gp41)

GWB-B4D6F2 0.2 mg Ask for price

Feline Immunodeficiency Virus gp95 Antibody

GWB-E938E9 0.25 mg Ask for price

OAEF00538-1MG - Feline Calicivirus Antibody

OAEF00538-1MG 1mg
EUR 1683

OAEF00539-1MG - Feline Calicivirus Antibody

OAEF00539-1MG 1mg
EUR 1683

OAEF00540-1MG - Feline Calicivirus Antibody

OAEF00540-1MG 1mg
EUR 1683

Hedgehog (Hh) ligands orchestrate tissue patterning and development by performing as morphogens, dictating totally different mobile responses relying on ligand focus. Cellular sensitivity to Hh ligands is influenced by heterotrimeric G protein exercise, which controls manufacturing of the second messenger 3′,5′-cyclic adenosine monophosphate (cAMP). cAMP in flip prompts Protein kinase A (PKA), which capabilities as an inhibitor and (uniquely in Drosophila) an activator of Hh signalling. A number of mammalian Gαi- and Gαs-coupled G protein-coupled receptors (GPCRs) have been proven to affect Sonic Hh (Shh) responses on this method. To decide if it is a extra basic phenomenon, we carried out an RNAi display screen concentrating on GPCRs in Drosophila RNAi-mediated depletion of greater than 40% of GPCRs examined both decreased or elevated Hh responsiveness in the growing Drosophila wing, carefully matching the results of Gαs and Gαi depletion, respectively.