A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines.

Emerging evidence indicates that microtubule-associated proteins (MAPs) are implicated in synaptic function; in particular, mice deficient for MAP6 exhibit striking deficits in plasticity and cognition. How MAP6 connects to plasticity mechanisms is unclear.

Here, we address the possible role of this protein in dendritic spines. We find that in MAP6-deficient cortical and hippocampal neurons, maintenance of mature spines is impaired, and can be restored by expressing a stretch of the MAP6 sequence called Mc modules.

G-5555

T11342L-1mg 1mg Ask for price
Description: G-5555

G-5555

T11342L-50mg 50mg Ask for price
Description: G-5555

G-5555

T11342L-5mg 5mg Ask for price
Description: G-5555

G-9791

T24078-10mg 10mg Ask for price
Description: G-9791

G-9791

T24078-1g 1g Ask for price
Description: G-9791

G-9791

T24078-1mg 1mg Ask for price
Description: G-9791

G-9791

T24078-50mg 50mg Ask for price
Description: G-9791

G-9791

T24078-5mg 5mg Ask for price
Description: G-9791

G-749

B2213-1 each
EUR 157.2

G-749

B2213-5 each
EUR 418.8

G-749

A8889-1 1 mg
EUR 129.6
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency.

G-749

A8889-5 5 mg
EUR 254.4
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency.

G-749

A8889-5.1 10 mM (in 1mL DMSO)
EUR 506.4
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency.

G-749

HY-12333 25mg
EUR 577.2

G-573

406200 250.0mg
EUR 350

G-749

406593 10.0mg
EUR 250

G-361

ABC-TC0265 1 vial Ask for price
Description: The cell line is established from a malignant melanoma of a 31 year old male Caucasian.

G-401

ABC-TC0266 1 vial Ask for price
Description: Wilms' tumor (embryonal carcinosarcoma of kidney).

G-402

ABC-TC0267 1 vial Ask for price
Description: Human Caucasian renal leiomyoblastoma. Derived from a tumour of a 9 month old female Caucasian. Highly transformed and grows in soft agar.

G-744

T15365-10mg 10mg Ask for price
Description: G-744

G-744

T15365-1g 1g Ask for price
Description: G-744

G-744

T15365-1mg 1mg Ask for price
Description: G-744

G-744

T15365-50mg 50mg Ask for price
Description: G-744

G-744

T15365-5mg 5mg Ask for price
Description: G-744

G-749

T2620-10mg 10mg Ask for price
Description: G-749

G-749

T2620-1g 1g Ask for price
Description: G-749

G-749

T2620-1mg 1mg Ask for price
Description: G-749

G-749

T2620-50mg 50mg Ask for price
Description: G-749

G-749

T2620-5mg 5mg Ask for price
Description: G-749

G-130

T27396-10mg 10mg Ask for price
Description: G-130

G-130

T27396-1g 1g Ask for price
Description: G-130

G-130

T27396-1mg 1mg Ask for price
Description: G-130

G-130

T27396-50mg 50mg Ask for price
Description: G-130

G-130

T27396-5mg 5mg Ask for price
Description: G-130

G-5555 (hydrochloride)

HY-19635A 10mg
EUR 280.8

G-5555 hydrochloride

T63719-10mg 10mg Ask for price
Description: G-5555 hydrochloride

G-5555 hydrochloride

T63719-1g 1g Ask for price
Description: G-5555 hydrochloride

G-5555 hydrochloride

T63719-1mg 1mg Ask for price
Description: G-5555 hydrochloride

G-5555 hydrochloride

T63719-50mg 50mg Ask for price
Description: G-5555 hydrochloride

G-5555 hydrochloride

T63719-5mg 5mg Ask for price
Description: G-5555 hydrochloride

Sephadex G-100 100g

17006001 EACH
EUR 714

Sephadex G-10 100g

17001001 EACH
EUR 346.8

Sephadex G-10 500g

17001002 EACH
EUR 1530

Sephadex G-15 100g

17002001 EACH
EUR 356.4

Sephadex G-75 100g

17005001 EACH
EUR 510

Sephadex G-100

abx082118-25g 25 g
EUR 526.8

G-418 (disulfate)

HY-17561 5g
EUR 325.2

G-418 disulfate

T6512-10mg 10mg Ask for price
Description: G-418 disulfate

G-418 disulfate

T6512-1g 1g Ask for price
Description: G-418 disulfate

G-418 disulfate

T6512-1mg 1mg Ask for price
Description: G-418 disulfate

G-418 disulfate

T6512-50mg 50mg Ask for price
Description: G-418 disulfate

G-418 disulfate

T6512-5mg 5mg Ask for price
Description: G-418 disulfate

G-418 SULFATE - 10g

PM-A4215/10 10g
EUR 244.42

G-15

B5469-10 10 mg
EUR 327.6
Description: G-15 is a selective antagonist of GPR30 with Ki value of 20 nM [1].G protein-coupled receptor 30 (GPR30) is an integral membrane protein that localizes to the endoplasmic reticulum and with high affinity for estradiol and aldosterone.

G-36

B5707-10 10 mg
EUR 327.6

G-36

407479 1.0mg
EUR 175

G-418 SULFATE - 1g

PM-A4215/1 1g
EUR 37.9

G-292 clone A141B1

ABC-TC0264 1 vial Ask for price
Description: Organism: Homo sapiens, human; Tissue: bone; Disease: osteosarcoma.

SEPHADEX G-25 FINE, 100 G

GE17-0032-01 EACH
EUR 386.4

G-418. Sulfate Solid

CR007-001 1 g
EUR 151.2

G-418. Sulfate Solid

CR007-005 5g
EUR 380.4

Sephadex G-100 Superfine 100g

17006101 EACH
EUR 894

Brilliant blue G-250

T20731-10mg 10mg Ask for price
Description: Brilliant blue G-250

Brilliant blue G-250

T20731-1g 1g Ask for price
Description: Brilliant blue G-250

Brilliant blue G-250

T20731-1mg 1mg Ask for price
Description: Brilliant blue G-250

Brilliant blue G-250

T20731-50mg 50mg Ask for price
Description: Brilliant blue G-250

Brilliant blue G-250

T20731-5mg 5mg Ask for price
Description: Brilliant blue G-250

Geneticin, G-418 Sulfate

A2513-1000 1 g
EUR 157.2
Description: G-418 is an elongation inhibitor of 80 S ribosomes [1].G418 is an aminoglycoside antibiotic, it has a wide spectrum of activity and is active against bacteria, yeasts, fungi, algae, plant and even animal cells.

Geneticin, G-418 Sulfate

A2513-5000 5 g
EUR 351.6
Description: G-418 is an elongation inhibitor of 80 S ribosomes [1].G418 is an aminoglycoside antibiotic, it has a wide spectrum of activity and is active against bacteria, yeasts, fungi, algae, plant and even animal cells.

10G Coomassie Blue G-250

NAT1362 10G
EUR 174

Sephadex G-25 Fine 100g

17003201 EACH
EUR 398.4

Sephadex G-25 Fine 500g

17003202 EACH
EUR 1725.6

Sephadex G-50 Fine 100g

17004201 EACH
EUR 465.6

Sephadex G-50 Fine 500g

17004202 EACH
EUR 2004

Autoseq G-50 1000 Columns

27534003 EACH
EUR 2092.8

Sephadex G-50 Dna Gr. 25 G

17057301 EACH
EUR 136.8

Sephadex G-25 Medium 100g

17003301 EACH
EUR 398.4

Sephadex G-25 Medium 500g

17003302 EACH
EUR 1736.4

Sephadex G-25 Coarse 100g

17003401 EACH
EUR 398.4

Sephadex G-25 Coarse 500g

17003402 EACH
EUR 1734

Sephadex G-50 Medium 100g

17004301 EACH
EUR 470.4

Sephadex G-50 Medium 500g

17004302 EACH
EUR 2145.6

Sephadex G-100 Dna Gr.100Gm

17057402 EACH
EUR 487.2

Sephadex G-25 Superfine 100g

17003101 EACH
EUR 462

Sephadex G-50 Superfine 100g

17004101 EACH
EUR 584.4

Sephadex G-75 Superfine 100g

17005101 EACH
EUR 704.4

50mg/mL G-418 Solution

PB180125-10mL 10 mL
EUR 55
Description: Supplements & Reagents

50 G G418 SULFATE, POWDER

61-234-RK 50 g/pk
EUR 1610.4
Description: Media Catalog; Cell Culture Reagents

Coomassie Blue G-250 2X

40340000-1 500 mL
EUR 37.64

Coomassie Blue G-250 2X

40340000-2 1 L
EUR 67.9

Anti-G gamma14 (1G11-C7)

YF-MA13281 100 ug
EUR 435.6
Description: Mouse monoclonal to G gamma14

Gel filtration medium G-100

T41039-10mg 10mg Ask for price
Description: Gel filtration medium G-100

Gel filtration medium G-100

T41039-1g 1g Ask for price
Description: Gel filtration medium G-100

Gel filtration medium G-100

T41039-1mg 1mg Ask for price
Description: Gel filtration medium G-100

Gel filtration medium G-100

T41039-50mg 50mg Ask for price
Description: Gel filtration medium G-100

Gel filtration medium G-100

T41039-5mg 5mg Ask for price
Description: Gel filtration medium G-100

Sephadex G-50

abx082119-25g 25 g
EUR 410.4

Sephadex G-25

abx082120-25g 25 g
EUR 410.4

G-25 SEPHADEX

IB06160 100GM
EUR 617.77

G-418 (Geneticin) Solution - 100ml

LM-A4115/100 100ml
EUR 134.31

G-418 (Geneticin) Solution - 20ml

LM-A4115/20 20ml
EUR 30.25

Express Coomassie Stain G-250

40340020-1 1 L
EUR 99.76

Express Coomassie Stain G-250

40340020-2 500 mL
EUR 68.06

Coomasie Brilliant Blue G-250

A2329-25G 25G
EUR 38.5
Description: Ultra Pure

Coomasie Brilliant Blue G-250

A2329-5G 5G
EUR 12.1
Description: Ultra Pure

Coomassie brilliant blue G-250

20-abx082402
  • EUR 276.00
  • EUR 226.80
  • 25 g
  • 5 g

Coomassie brilliant blue G-250

20-abx082562
  • EUR 260.40
  • EUR 210.00
  • 25 g
  • 5 g

Coomassie brilliant blue G-250

CB0038 25g
EUR 90.28

Coomassie Brilliant Blue G-250

09409-42 25G
EUR 38.5

Coomassie Brilliant Blue G-250

40340008-1 10 g
EUR 21.12

Coomassie Brilliant Blue G-250

40340008-2 25 g
EUR 37.64

Coomassie Brilliant Blue G-250

40340008-3 50 g
EUR 68.46

Coomassie Brilliant Blue G-250

40340008-4 100 g
EUR 127.66

Sephadex G-50 M Dna Grade 100Gm

17004502 EACH
EUR 378

Pd Spintrap G-25

28918004 EACH
EUR 323.76

Pd Minitrap G-25

28918007 EACH
EUR 396.72

Pd Miditrap G-25

28918008 EACH
EUR 396.72

Pd Minitrap G-10

28918010 EACH
EUR 458.4

PD MIDITRAP G-10

GE28-9180-11 EACH
EUR 505.2

Pd Multitrap G-25

28918006 EACH
EUR 923.4

PudexTM G-25 Fine

E233-60115-27 25 g
EUR 221.25

PudexTM G-25 Fine

E233-60115-28 100 g
EUR 442.5

PudexTM G-25 Fine

E233-60115-29 500 g
EUR 1492.5

PudexTM G-25 Fine

E233-60115-30 1 kg
EUR 2475

Coomassie Blue G-250 Staining Solution

GR103035 1 L
EUR 95

G-5555 hydrochloride (1648863-90-4 free base)

T11342-10mg 10mg Ask for price
Description: G-5555 hydrochloride (1648863-90-4 free base)

G-5555 hydrochloride (1648863-90-4 free base)

T11342-1g 1g Ask for price
Description: G-5555 hydrochloride (1648863-90-4 free base)

G-5555 hydrochloride (1648863-90-4 free base)

T11342-1mg 1mg Ask for price
Description: G-5555 hydrochloride (1648863-90-4 free base)

G-5555 hydrochloride (1648863-90-4 free base)

T11342-50mg 50mg Ask for price
Description: G-5555 hydrochloride (1648863-90-4 free base)

G-5555 hydrochloride (1648863-90-4 free base)

T11342-5mg 5mg Ask for price
Description: G-5555 hydrochloride (1648863-90-4 free base)

PudexTM G-25 Corase

E233-60113-27 25 g
EUR 195

PudexTM G-25 Corase

E233-60113-28 100 g
EUR 405

PudexTM G-25 Corase

E233-60113-29 500 g
EUR 1342.5

PudexTM G-25 Corase

E233-60113-30 1 kg
EUR 2175

PudexTM G-25 Corase

E233-60113-41 5kg
EUR 10875

PudexTM G-25 Medium

E233-60114-27 25 g
EUR 195

PudexTM G-25 Medium

E233-60114-28 100 g
EUR 405

PudexTM G-25 Medium

E233-60114-29 500 g
EUR 1342.5

PudexTM G-25 Medium

E233-60114-30 1 kg
EUR 2175

PudexTM G-25 Medium

E233-60114-41 5kg
EUR 10875

RABBIT BRAIN ACETONE POWDER (200-g)

41110-2 200g
EUR 1942.85

PudexTM G-25 Superfine

E233-60116-27 25 g
EUR 255

PudexTM G-25 Superfine

E233-60116-28 100 g
EUR 495

PudexTM G-25 Superfine

E233-60116-29 500 g
EUR 1680

PudexTM G-25 Superfine

E233-60116-30 1 kg
EUR 2812.5

Anti-G protein alpha Inhibitor 2 (3G11)

YF-MA13271 100 ug
EUR 435.6
Description: Mouse monoclonal to G protein alpha Inhibitor 2

Chicken β2-glycoprotein 1 IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

NSL1205Ch 1300 T
EUR 528

SEPHADEX G-50, SUPERFINE

IB06150 100GM
EUR 609.14

Rat β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

CN-01778R1 96T
EUR 567.6

Rat β2-glycoprotein 1 antibody IgA/G/M,β2-GP2 IgA/G/M ELISA Kit

CN-01778R2 48T
EUR 387.6

Rat β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0099RT-48T 48T
EUR 380.4

Rat β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0099RT-96T 96T
EUR 595.2

Rat β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA0817RA-48T 48T
EUR 465

Rat β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA0817RA-96T 96T
EUR 600

Rat β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

QY-E11554 96T
EUR 433.2

Mouse β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

CN-02656M1 96T
EUR 523.2

Mouse β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

CN-02656M2 48T
EUR 344.4

Human β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0515HM-48T 48T
EUR 346.8

Human β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0515HM-96T 96T
EUR 559.2

Mouse β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0332MS-48T 48T
EUR 403.2

Mouse β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

GA-E0332MS-96T 96T
EUR 640.8

Mouse β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA0770MO-48T 48T
EUR 465

Mouse β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA0770MO-96T 96T
EUR 600

Mouse β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

QY-E21641 96T
EUR 433.2

Human β2-glycoprotein 1 antibody IgA/G/M(β2-GP1 IgA/G/M)ELISA Kit

QY-E04423 96T
EUR 433.2

Human β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA2245HU-48T 48T
EUR 435

Human β2-glycoprotein 1 antibody IgA/G/M,β2-GP1 IgA/G/M ELISA Kit

YLA2245HU-96T 96T
EUR 562.5

Rabbit BRAIN ACETONE POWDER VARISENS(250-g)

41170-1 250 g
EUR 3892.51

TAN Std 0.5mg/g KOH in Synth Oil 100g

RETAN05S PK3
EUR 672

TAN Std 1.0mg/g KOH in Synth Oil 100g

RETAN10S PK3
EUR 672

TAN Std 1.5mg/g KOH in Synth Oil 100g

RETAN15S PK3
EUR 672

TAN Std 2.0mg/g KOH in Synth Oil 100g

RETAN20S PK3
EUR 672

TAN Std 2.5mg/g KOH in Synth Oil 100g

RETAN25S PK3
EUR 672

TAN Std 3.0mg/g KOH in Synth Oil 100g

RETAN30S PK3
EUR 672

TAN Std 4.5mg/g KOH in Synth Oil 100g

RETAN45S PK3
EUR 672

TBN Std 1.0mg/g KOH in Synth Oil 100g

RETBN1S PK3
EUR 672

TBN Std 3.0mg/g KOH in Synth Oil 100g

RETBN3S PK3
EUR 682.83

TBN Std 6.0mg/g KOH in Synth Oil 100g

RETBN6S PK3
EUR 672

TBN Std 15mg/g KOH in Synth Oil 100g

RETBN15S PK3
EUR 682.83

TBN Std 30mg/g KOH in Synth Oil 100g

RETBN30S PK3
EUR 672

TBN Std 40mg/g KOH in Synth Oil 100g

RETBN40S PK3
EUR 672

TBN Std 70mg/g KOH in Synth Oil 100g

RETBN70S PK3
EUR 672

G-418. Sulfate, 100mg/ml, Sterile-Filtered Solution

CR008-001 10 ml
EUR 171.6

PrePack Pudex G-25 Superfine

E234-60116-02 5×5 mL kit(PrePack Pudex G-25 Superfine)
EUR 375

PrePack Pudex G-25 Superfine

E234-60116-16 1×5 mL kit(PrePack Pudex G-25 Superfine)
EUR 82.5

illustra Sephadex G-25 DNA Grade SF pack of 100g

17057202 EACH
EUR 330

HBV Surface Antigen (subtype ayw, mutation G-145-R)

DAG1468 50 ug
EUR 889.2

HBV Surface Antigen (subtype adw, mutation G-145-R

DAG3933 50 ug
EUR 889.2

Sephadex® G-100 for gel filtration 40-120 micron

S02255 10G
EUR 883.51

SuperPower (TM) Stain Tablet, Fast Staining Coomassie G-250

DG-STAIN 5drytablets, 5prep
EUR 192.24

Bovine LUNG ACETONE POWDER (50-g)*

57053-2 50 g
EUR 991.5

Cytiva AutoSeq G-50 Columns PK250

27534002 EACH
EUR 828

Recombinant HBV S Protein (Subtype ayw, Mutation G-145-R)

VAng-Lsx0177-50g 50 µg
EUR 1316.4
Description: HBV Surface Antigen (subtype ayw, mutation G-145-R), recombinant protein from P. pastoris.

Recombinant HBV S Protein (Subtype adw, Mutation G-145-R)

VAng-Lsx0191-inquire inquire Ask for price
Description: HBV Surface Antigen (subtype adw, mutation G-145-R), recombinant protein from P. pastoris.

Mc modules directly bind actin filaments and mediate activity-dependent stabilisation of F-actin in dendritic spines, a key event of synaptic plasticity. In vitro, Mc modules enhance actin filament nucleation and promote the formation of stable, highly ordered filament bundles. Activity-induced phosphorylation of MAP6 likely controls its transfer to the spine cytoskeleton.