Emerging evidence indicates that microtubule-associated proteins (MAPs) are implicated in synaptic function; in particular, mice deficient for MAP6 exhibit striking deficits in plasticity and cognition. How MAP6 connects to plasticity mechanisms is unclear.
Here, we address the possible role of this protein in dendritic spines. We find that in MAP6-deficient cortical and hippocampal neurons, maintenance of mature spines is impaired, and can be restored by expressing a stretch of the MAP6 sequence called Mc modules.
Safe-Red™ |
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G108-R | ABM | 1.0 ml | EUR 71 |
Safe-White™ |
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G108-W | ABM | 1.0 ml | EUR 71 |
Goat Immunoglobulin G (IgG) ELISA Kit |
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DLR-IgG-g-48T | DL Develop | 48T | EUR 464 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Goat Immunoglobulin G (IgG) ELISA Kit |
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DLR-IgG-g-96T | DL Develop | 96T | EUR 601 |
Description: A competitive inhibition quantitative ELISA assay kit for detection of Goat Immunoglobulin G (IgG) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Goat Immunoglobulin G (IgG) ELISA Kit |
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RDR-IgG-g-48Tests | Reddot Biotech | 48 Tests | EUR 482 |
Goat Immunoglobulin G (IgG) ELISA Kit |
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RDR-IgG-g-96Tests | Reddot Biotech | 96 Tests | EUR 667 |
Histamine [G-BSA] (G-G-BSA) |
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DAG3327 | Creative Diagnostics | 1mg | EUR 1234 |
Hepatitis Surface Antigen subtype Ayw Mutant G-145-R (HBsAg Ayw mutant), Recombinant (P. Pastoris), purified |
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HBA29-G-145R | Alpha Diagnostics | 50 ug | EUR 347 |
Nipah virus Glycoprotein G (G) |
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1-CSB-CF862323NDT | Cusabio |
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Description: Recombinant Nipah virus Glycoprotein G(G) expressed in in vitro E.coli expression system |
Adipokinetic Hormone, G (AKH-G) |
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5-00610 | CHI Scientific | 4 x 5mg | Ask for price |
Cyclin G (Cyclin G) Antibody |
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20-abx013056 | Abbexa |
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Cyclin G (Cyclin G) Antibody |
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abx232129-100ug | Abbexa | 100 ug | EUR 481 |
G-R-G-D-S-P |
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5-01166 | CHI Scientific | 4 x 5mg | Ask for price |
G-R-G-D-T-P |
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5-01167 | CHI Scientific | 4 x 5mg | Ask for price |
G-R-G-E-T-P |
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5-01169 | CHI Scientific | 4 x 5mg | Ask for price |
Protein Kinase G Substrate; G-Subtide |
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5-01842 | CHI Scientific | 4 x 5mg | Ask for price |
R-G-Y-S-L-G |
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5-01863 | CHI Scientific | 4 x 5mg | Ask for price |
Leukocyte Antigen G (HLA-G) Antibody |
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20-abx109883 | Abbexa |
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Peptidylprolyl Isomerase G (Cyclophilin G) Antibody |
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20-abx114386 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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20-abx320348 | Abbexa |
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Major Surface Glycoprotein G (G) Antibody |
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20-abx317831 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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abx034168-400ul | Abbexa | 400 ul | EUR 523 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx034168-80l | Abbexa | 80 ยตl | EUR 286 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx034899-100ul | Abbexa | 100 ul | EUR 523 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx034900-400ul | Abbexa | 400 ul | EUR 523 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx034900-80l | Abbexa | 80 ยตl | EUR 286 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139500-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139501-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139502-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139503-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139504-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139505-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139506-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139507-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139508-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139510-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139511-01mg | Abbexa | 0.1 mg | EUR 481 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx139512-01mg | Abbexa | 0.1 mg | EUR 439 |
Leukocyte Antigen G (HLA-G) Antibody |
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20-abx136098 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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20-abx005635 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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20-abx009168 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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abx413633-02mg | Abbexa | 0.2 mg | EUR 648 |
Leukocyte Antigen G (HLA-G) Antibody |
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abx413634-02mg | Abbexa | 0.2 mg | EUR 648 |
Adipokinetic Hormone, G (AKH-G) Peptide |
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20-abx266348 | Abbexa |
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Protein Kinase G Substrate; G-Subtide |
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20-abx265631 | Abbexa |
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Endonuclease G, Mitochondrial (Endo G) Antibody |
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20-abx215156 | Abbexa |
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Leukocyte Antigen G (HLA-G) Antibody |
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20-abx215947 | Abbexa |
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G Antibody |
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1-CSB-PA006050GA01HU | Cusabio |
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Description: A polyclonal antibody against G. Recognizes G from Human. This antibody is Unconjugated. Tested in the following application: ELISA |
G Antibody |
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1-CSB-PA14899A0Rb | Cusabio |
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Description: A polyclonal antibody against G. Recognizes G from Rabies virus. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:1000-1:5000 |
G Antibody |
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1-CSB-PA365937LA01HPO | Cusabio |
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Description: A polyclonal antibody against G. Recognizes G from Human respiRatory syncytial virus A. This antibody is Unconjugated. Tested in the following application: ELISA |
G Antibody |
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1-CSB-PA389005LA01RIE | Cusabio |
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Description: A polyclonal antibody against G. Recognizes G from Rabies virus. This antibody is Unconjugated. Tested in the following application: ELISA |
Protein G |
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P6872 | Bio Basic | 5mg | EUR 137 |
G-5555 |
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HY-19635 | MedChemExpress | 50mg | EUR 785 |
G-1 |
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HY-107216 | MedChemExpress | 10mg | EUR 360 |
G-749 |
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HY-12333 | MedChemExpress | 25mg | EUR 481 |
Thiamet G |
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HY-12588 | MedChemExpress | 50mg | EUR 601 |
Alisol G |
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HY-N0855 | MedChemExpress | 10mg | EUR 739 |
Gomisin G |
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HY-N0858 | MedChemExpress | 10mg | EUR 739 |
Tenacissoside G |
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HY-N2103 | MedChemExpress | 1mg | EUR 179 |
Hosenkoside G |
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HY-N2242 | MedChemExpress | 1mg | EUR 313 |
Rebaudioside G |
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HY-N2291 | MedChemExpress | 1mg | EUR 379 |
Saikosaponin G |
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HY-N4216 | MedChemExpress | 1mg | EUR 443 |
Kuwanon G |
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HY-N4247 | MedChemExpress | 10mg | EUR 436 |
G-CSF |
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E21-002 | EnoGene | 10ug | EUR 343 |
Cathepsin G |
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MO20021 | Neuromics | 100 ul | EUR 213 |
Antagonist G |
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5-00704 | CHI Scientific | 0.4 x 5mg | Ask for price |
Conantokin G |
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5-00989 | CHI Scientific | 4 x 1mg | Ask for price |
G-Q |
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5-01165 | CHI Scientific | 4 x 5mg | Ask for price |
W-G |
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5-02089 | CHI Scientific | 4 x 5mg | Ask for price |
Sulforhodamine g |
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80102 | Biotium | 5G | EUR 165 |
Description: Minimum order quantity: 1 unit of 5G |
Protein G |
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abx670070-5mg | Abbexa | 5 mg | EUR 759 |
Protein G |
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abx670076-1mg | Abbexa | 1 mg | EUR 495 |
Antagonist G |
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B5243-1 | ApexBio | 1 mg | EUR 340 |
G-1 |
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B5455-10 | ApexBio | 10 mg | EUR 273 |
Description: G-1 is a potent and selective agonist of GPR30 with EC50 value of 2 nM [1].G protein-coupled receptor 30 (GPR30) is an integral membrane protein that localizes to the endoplasmic reticulum and with high affinity for estradiol and aldosterone. |
G-15 |
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B5469-10 | ApexBio | 10 mg | EUR 273 |
Description: G-15 is a selective antagonist of GPR30 with Ki value of 20 nM [1].G protein-coupled receptor 30 (GPR30) is an integral membrane protein that localizes to the endoplasmic reticulum and with high affinity for estradiol and aldosterone. |
Conantokin G |
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B5533-.5 | ApexBio | 500 ug | EUR 399 |
G-36 |
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B5707-10 | ApexBio | 10 mg | EUR 273 |
Thiamet G |
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B2048-25 | ApexBio | 25 mg | EUR 350 |
Description: Thiamet G is a potent and selective inhibitor of O-GlcNAcase with Ki value of 21 nM [1].O-GlcNAcase is an enzyme that removes GlcNAc from proteins. |
Thiamet G |
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B2048-5 | ApexBio | 5 mg | EUR 128 |
Description: Thiamet G is a potent and selective inhibitor of O-GlcNAcase with Ki value of 21 nM [1].O-GlcNAcase is an enzyme that removes GlcNAc from proteins. |
Thiamet G |
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B2048-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 131 |
Description: Thiamet G is a potent and selective inhibitor of O-GlcNAcase with Ki value of 21 nM [1].O-GlcNAcase is an enzyme that removes GlcNAc from proteins. |
Tenacissoside G |
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N2128-20 | ApexBio | 20 mg | EUR 282 |
Description: Extractedย fromย Marsdenia tenacissima (Roxb.) Wight et Arn.;Storeย theย productย inย sealed,ย coolย andย dryย condition |
g-Endorphin |
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H-2725.0001 | Bachem | 1.0mg | EUR 151 |
Description: Sum Formula: C83H131N19O27S; CAS# [60893-02-9] |
g-Endorphin |
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H-2725.0005 | Bachem | 5.0mg | EUR 515 |
Description: Sum Formula: C83H131N19O27S; CAS# [60893-02-9] |
Neuropeptide g |
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H-7455.0500 | Bachem | 0.5mg | EUR 181 |
Description: Sum Formula: C99H158N34O29S; CAS# [114882-65-4] net |
Neuropeptide g |
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H-7455.1000 | Bachem | 1.0mg | EUR 300 |
Description: Sum Formula: C99H158N34O29S; CAS# [114882-65-4] net |
G-749 |
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A8889-1 | ApexBio | 1 mg | EUR 108 |
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency. |
G-749 |
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A8889-5 | ApexBio | 5 mg | EUR 212 |
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency. |
G-749 |
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A8889-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 422 |
Description: G-749 is a selective inhibitor of Fms-like tyrosine receptor kinase-3 (FLT3) with IC50 value of 0.4 nM for wild-type FLT31.G-749 is a synthesized and ATP-competitive inhibitor of wild-type FLT3 with high potency. |
G-CaMP3 |
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PVT14629 | Lifescience Market | 2 ug | EUR 703 |
pLTR- G |
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PVT11136 | Lifescience Market | 2 ug | EUR 266 |
Sophoraflavanone G |
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TB02920 | ChemNorm | 10mg | EUR 228 |
Tenacissoside G |
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TB0420-0020 | ChemNorm | 25mg | EUR 355 |
Gomisin G |
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TB0551-0020 | ChemNorm | 10mg | EUR 355 |
Hosenkoside G |
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TB0882-0025 | ChemNorm | 10mg | EUR 484 |
Negsehisandrin G |
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TB0907-0100 | ChemNorm | 0.05ml | EUR 526 |
Rebaudioside G |
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TBW00142 | ChemNorm | 10mg | EUR 484 |
Mc modules directly bind actin filaments and mediate activity-dependent stabilisation of F-actin in dendritic spines, a key event of synaptic plasticity. In vitro, Mc modules enhance actin filament nucleation and promote the formation of stable, highly ordered filament bundles. Activity-induced phosphorylation of MAP6 likely controls its transfer to the spine cytoskeleton.