During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons and it is unknown how this process is controlled.
 ACPT-II |
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B6601-10 |
ApexBio |
10 mg |
EUR 293 |
ACPT-II |
|
B6601-5 |
ApexBio |
5 mg |
EUR 196 |
ACPT-II |
|
B6601-50 |
ApexBio |
50 mg |
EUR 1024 |
 ACPT-I |
|
B5051-10 |
ApexBio |
10 mg |
EUR 318 |
ACPT-I |
|
B5051-25 |
ApexBio |
25 mg |
EUR 659 |
ACPT-I |
|
B5051-5 |
ApexBio |
5 mg |
EUR 196 |
 anti-ACPT |
|
YF-PA21789 |
Abfrontier |
50 ul |
EUR 363 |
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Description: Mouse polyclonal to ACPT |
 ACPT antibody |
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70R-7296 |
Fitzgerald |
50 ug |
EUR 467 |
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Description: Rabbit polyclonal ACPT antibody raised against the middle region of ACPT |
 anti- ACPT antibody |
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FNab00103 |
FN Test |
100µg |
EUR 548.75 |
|
|
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Description: Antibody raised against ACPT |
 ACPT Conjugated Antibody |
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C37143 |
SAB |
100ul |
EUR 397 |
 ACPT Blocking Peptide |
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33R-9175 |
Fitzgerald |
100 ug |
EUR 180 |
|
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ACPT antibody, catalog no. 70R-7296 |
 Human ACPT shRNA Plasmid |
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20-abx964222 |
Abbexa |
|
|
|
|
) ACPT Recombinant Protein (Mouse) |
|
RP113918 |
ABM |
100 ug |
Ask for price |
) ACPT Recombinant Protein (Rat) |
|
RP188942 |
ABM |
100 ug |
Ask for price |
) ACPT Recombinant Protein (Human) |
|
RP045694 |
ABM |
100 ug |
Ask for price |
 Antibody) Acid Phosphatase, Testicular (ACPT) Antibody |
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abx037579-100ug |
Abbexa |
100 ug |
EUR 391 |
|
|
Acid Phosphatase, Testicular (ACPT) Antibody |
|
abx230103-100ug |
Abbexa |
100 ug |
EUR 509 |
|
|
 (pORF)) ACPT ORF Vector (Human) (pORF) |
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ORF015232 |
ABM |
1.0 ug DNA |
Ask for price |
 (pORF)) Acpt ORF Vector (Mouse) (pORF) |
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ORF037974 |
ABM |
1.0 ug DNA |
EUR 506 |
 (pORF)) Acpt ORF Vector (Rat) (pORF) |
|
ORF062982 |
ABM |
1.0 ug DNA |
EUR 506 |
) ACPT sgRNA CRISPR Lentivector set (Human) |
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K0031801 |
ABM |
3 x 1.0 ug |
EUR 339 |
) Acpt sgRNA CRISPR Lentivector set (Mouse) |
|
K3032801 |
ABM |
3 x 1.0 ug |
EUR 339 |
) Acpt sgRNA CRISPR Lentivector set (Rat) |
|
K6218901 |
ABM |
3 x 1.0 ug |
EUR 339 |
 ELISA Kit) Human Acid Phosphatase, Testicular (ACPT) ELISA Kit |
|
abx385591-96tests |
Abbexa |
96 tests |
EUR 911 |
|
|
) Recombinant Salmonella acpT Protein (aa 1-192) |
|
VAng-Wyb0921-1mgEcoli |
Creative Biolabs |
1 mg (E. coli) |
EUR 3630 |
|
Description: Salmonella typhi 4'-phosphopantetheinyl transferase AcpT, recombinant protein. |
Recombinant Salmonella acpT Protein (aa 1-192) |
|
VAng-Wyb0921-500gEcoli |
Creative Biolabs |
500 µg (E. coli) |
EUR 2460 |
|
Description: Salmonella typhi 4'-phosphopantetheinyl transferase AcpT, recombinant protein. |
Recombinant Salmonella acpT Protein (aa 1-192) |
|
VAng-Wyb0921-50gEcoli |
Creative Biolabs |
50 µg (E. coli) |
EUR 1676 |
|
Description: Salmonella typhi 4'-phosphopantetheinyl transferase AcpT, recombinant protein. |
 (Target 1)) ACPT sgRNA CRISPR Lentivector (Human) (Target 1) |
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K0031802 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 2)) ACPT sgRNA CRISPR Lentivector (Human) (Target 2) |
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K0031803 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 3)) ACPT sgRNA CRISPR Lentivector (Human) (Target 3) |
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K0031804 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 1)) Acpt sgRNA CRISPR Lentivector (Mouse) (Target 1) |
|
K3032802 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 2)) Acpt sgRNA CRISPR Lentivector (Mouse) (Target 2) |
|
K3032803 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 3)) Acpt sgRNA CRISPR Lentivector (Mouse) (Target 3) |
|
K3032804 |
ABM |
1.0 ug DNA |
EUR 154 |
 Human Testicular acid phosphatase, ACPT ELISA KIT |
|
ELI-19713h |
Lifescience Market |
96 Tests |
EUR 824 |
 (Target 1)) Acpt sgRNA CRISPR Lentivector (Rat) (Target 1) |
|
K6218902 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 2)) Acpt sgRNA CRISPR Lentivector (Rat) (Target 2) |
|
K6218903 |
ABM |
1.0 ug DNA |
EUR 154 |
 (Target 3)) Acpt sgRNA CRISPR Lentivector (Rat) (Target 3) |
|
K6218904 |
ABM |
1.0 ug DNA |
EUR 154 |
 (pPB-His-MBP)) ACPT Protein Vector (Human) (pPB-His-MBP) |
|
PV319302 |
ABM |
500 ng |
Ask for price |
 (pPB-His-GST)) ACPT Protein Vector (Human) (pPB-His-GST) |
|
PV319303 |
ABM |
500 ng |
Ask for price |
 (pPB-C-His)) ACPT Protein Vector (Human) (pPB-C-His) |
|
PV060925 |
ABM |
500 ng |
Ask for price |
 (pPB-N-His)) ACPT Protein Vector (Human) (pPB-N-His) |
|
PV060926 |
ABM |
500 ng |
Ask for price |
 (pPM-C-HA)) ACPT Protein Vector (Human) (pPM-C-HA) |
|
PV060927 |
ABM |
500 ng |
Ask for price |
 (pPM-C-His)) ACPT Protein Vector (Human) (pPM-C-His) |
|
PV060928 |
ABM |
500 ng |
Ask for price |
 (pPB-C-His)) ACPT Protein Vector (Rat) (pPB-C-His) |
|
PV251926 |
ABM |
500 ng |
EUR 603 |
 (pPB-N-His)) ACPT Protein Vector (Rat) (pPB-N-His) |
|
PV251927 |
ABM |
500 ng |
EUR 603 |
 (pPM-C-HA)) ACPT Protein Vector (Rat) (pPM-C-HA) |
|
PV251928 |
ABM |
500 ng |
EUR 603 |
 (pPM-C-His)) ACPT Protein Vector (Rat) (pPM-C-His) |
|
PV251929 |
ABM |
500 ng |
EUR 603 |
 Acpt 3'UTR Luciferase Stable Cell Line |
|
TU101290 |
ABM |
1.0 ml |
Ask for price |
 (pPB-C-His)) ACPT Protein Vector (Mouse) (pPB-C-His) |
|
PV151894 |
ABM |
500 ng |
EUR 603 |
 (pPB-N-His)) ACPT Protein Vector (Mouse) (pPB-N-His) |
|
PV151895 |
ABM |
500 ng |
EUR 603 |
 (pPM-C-HA)) ACPT Protein Vector (Mouse) (pPM-C-HA) |
|
PV151896 |
ABM |
500 ng |
EUR 603 |
 (pPM-C-His)) ACPT Protein Vector (Mouse) (pPM-C-His) |
|
PV151897 |
ABM |
500 ng |
EUR 603 |
 Acpt 3'UTR GFP Stable Cell Line |
|
TU250186 |
ABM |
1.0 ml |
Ask for price |
Acpt 3'UTR Luciferase Stable Cell Line |
|
TU200186 |
ABM |
1.0 ml |
Ask for price |
 ACPT 3'UTR GFP Stable Cell Line |
|
TU050190 |
ABM |
1.0 ml |
EUR 1394 |
Acpt 3'UTR GFP Stable Cell Line |
|
TU151290 |
ABM |
1.0 ml |
Ask for price |
 ACPT 3'UTR Luciferase Stable Cell Line |
|
TU000190 |
ABM |
1.0 ml |
EUR 1394 |
 (pPM-N-D-C-HA)) ACPT Protein Vector (Human) (pPM-N-D-C-HA) |
|
PV319304 |
ABM |
500 ng |
Ask for price |
 (pPM-N-D-C-His)) ACPT Protein Vector (Human) (pPM-N-D-C-His) |
|
PV319305 |
ABM |
500 ng |
Ask for price |
) ACPT sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
|
K0031805 |
ABM |
3 x 1.0 ug |
EUR 376 |
) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
|
K3032805 |
ABM |
3 x 1.0 ug |
EUR 376 |
) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
|
K6218905 |
ABM |
3 x 1.0 ug |
EUR 376 |
 (Target 1)) ACPT sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
|
K0031806 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 2)) ACPT sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
|
K0031807 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 3)) ACPT sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
|
K0031808 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 1)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
|
K3032806 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 2)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
|
K3032807 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 3)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
|
K3032808 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 1)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
|
K6218906 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 2)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
|
K6218907 |
ABM |
1.0 ug DNA |
EUR 167 |
 (Target 3)) Acpt sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
|
K6218908 |
ABM |
1.0 ug DNA |
EUR 167 |
Here, we use single molecule fluorescent in situ hybridisation to show that larval neurons selectively transcribe a long prospero mRNA isoform containing a 15 kb 3′ untranslated region, which is bound in the brain by the conserved RNA-binding protein Syncrip/hnRNPQ.
Syncrip binding increases the mRNA stability of the long prospero isoform, which allows an upregulation of Prospero protein production. Adult flies selectively lacking the long prospero isoform show abnormal behaviour that could result from impaired locomotor or neurological activity.
