abexxa antibodies

New radiation reagents:

  • 03021679799 Uv Radiation Resistance Associated Gene Antibody
    50 μl
  • 02021679799 Uv Radiation Resistance Associated Gene Antibody
    150 μl
  • 01011389976 Mouse X-ray radiation resistance-associated protein 1 (XRRA1) ELISA Kit
    1x plate of 96 wells
  • TLR-4 antibodies
  • 01011395403 ELISA test for Mouse X-ray radiation resistance-associated protein 1 (XRRA1)

X-Ray Crystallography of Antibodies by Dr. Eduardo A. Padlan

The detailed structure of antibodies and various fragments, including
isolated domains, from different isotypes and from different species has
become available from X-ray crystallography. Also, amino acid and
nucleotide sequence data have been obtained for thousands of different
chains (Kabat et al., 1991), so that a detailed correlation of primary and
three-dimensional structures can be performed. With this wealth of
information, we can now begin to understand the biological functions of
antibodies in structural terms.

Stationary High Stability X-Ray Equipment used:


Genotoxicity evaluation of two kinds of smoke-water and 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one. (2012)

Smoke, smoke-water and aerosols have a stimulatory effect on seed germination and growth vigour of many seedlings, making them potentially useful for different purposes, provided they do not pose a health risk. Therefore, the genotoxicity of two kinds of smoke-water and 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one, a variant of the most active smoke compound (3-methyl-2H-furo[2,3-c]pyran-2-one) was evaluated using the Vitotox assay. Smoke-water extracts were obtained from burning leaves: Themeda triandra (smoke-water Tt) and a mix of Themeda triandra and Passerina vulgaris (smoke-water Kb). No genotoxic effect was observed for any of the three samples. However, the three samples are toxic at the highest concentrations (3,7-dimethyl-2H-furo[2,3-c]pyran-2-one, 2 ppm; smoke-water Tt, dilutions 1 : 1, 1 : 2, 1 : 4; smoke-water Kb, dilution 1 : 1) without addition of S9 mix. Both the butenolide 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one and smoke-water Tt are also toxic at high doses in the presence of S9 (2 ppm and dilutions 1 : 1 and 1 : 2, respectively), but not smoke-water Kb. Thus, from these results, no genotoxicity of these three samples can be assumed, which is accordance with the previous tests performed with 3-methyl-2H-furo[2,3-c]pyran-2-one and a smoke-water>

Gentoxicity testing, Lieven Gevaert
Journal Of Applied Toxicology

ArticleinJournal of Applied Toxicology 30(6):596-602 · August 2010

Available on ResearchGate